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Apparently weird incel types think oestrogen is responsible for women’s sex drive.

I suspect it would blow their minds if they ever found out that the hormone most involved in making women horny is actually testosterone.

They act like we’re a different species or something. We all have the same set of receptors, more or less, guys. That’s why medical transition is even possible.

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in reply to Sarah Brown

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in reply to Sarah Brown

Being serious here, it would likely be much better if we stopped gendering gonadal steroids quite so much. The physical characteristics we regard as “male” and “female” are just the result of variances in endocrine system mixes which aren’t as polar as most people assume, and actually overlap, and short of direct reproduction, you can program nearly any human body to develop pretty much any of these different phenotype expressions: just change the mix. Trans people do it all the time. The number of people who assume that, eg, trans women’s tits are all implants (they aren’t) and can’t lactate (they can) is sad. Surely it’s better if we all understand our own biology a bit better?
in reply to Sarah Brown

To make it even funnier:
Hormones act thru "hormones receptors" which are proteins - coded in our genes as all proteins.
The testosterone receptor is actually coded on the X chromosome ( check at https://en.wikipedia.org/wiki/Androgen_receptor ) - the female chromosome - which means that women have 2 copies of it while men only one !
in reply to Sarah Brown

The big realisation for me was that none of these hormones actually do anything in themselves. They’re just messengers.
in reply to Richard Gadsden

@po8crg @ajlanes even then, you still have hormones. neurotransmitters are defined functionally rather than geographically
in reply to Adam

@Adam @Alexandra Lanes @Richard Gadsden yeah. AIUI, histamine used to be considered a hormone until its mechanism of action was better understood and it was realised that it is actually a neurotransmitter
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Sarah Brown

@Alisdair Calder McGregor I mean, this isn’t particularly advanced. It’s just “hypothalamus makes GnRH, pituitary receives GnRH and makes LH, gonads receive LH and make testosterone, testosterone encounters aromatise and turns into oestrogen, hypothalamus notices testosterone and oestrogen and makes less GnRH in response”

A makes B makes C makes D makes less A 🤷🏻‍♀️

in reply to Sarah Brown

@Alisdair Calder McGregor and without C, you are less inclined to do sexytimes, and without D your bones fall to bits.
in reply to Sarah Brown

or TERFs who say that testosterone in trans men a) kills libido and b) it makes it impossible to orgasm. Tell me you've never spoken to any trans men without explicitly saying so 😂
in reply to Llwynog

@Llwynog “Hi. I’ve started T. I’m just going into the bathroom for … reasons. I will be out when I am hypoglycaemic, with friction burns”
in reply to Sarah Brown

honestly, I know trans guys who, during the first months on T, got into trouble for missing lectures and being late to work because they were...busy 😅